Inform Yourself About Cicatricial Alopecia

Inform Yourself About Cicatricial Alopecia
Alopecia Areata is an autoimmune disease. The initial lesion is usually a totally bald, smooth patch. At its margins, hairs which appear normal may also be very readily extracted. Subsequent progress is variable. The course of alopecia areata is highly unpredictable, and the uncertainty of what will happen next is probably the most difficult and frustrating aspect of the disease. You may continue to lose hair, or your hair loss may stop. The hair you have lost may or may not grow back, and you may or may not continue to develop new bare patches.
One of the Alopecia Areata types is Cicatricial alopecia . It can be caused by a range of rare disorders related to the destruction of the hair follicle, which gets replaced by scar tissue which may lead to permanent hair loss. The hair loss is usually gradual, without symptoms, and can be unnoticed for long periods. Some people experience hair loss with progressive symptoms such as itching, burning and pain. The inflammation that destroys the follicle is located below the surface of the skin and there is usually no "scar" seen on the scalp. Affected areas of the scalp may show little signs of inflammation.
There are two known types of cicatricial alopecias classified as primary Cicatricial alopecia or secondary Cicatricial alopecia. For primary cicatricial alopecia in the hair follicle is the target of the destructive inflammatory process. In secondary cicatricial alopecia, destruction of the hair follicle is an "accidental" non-follicle-directed process or external injury, such as severe infections, burns, radiation, or tumors.
Primary Cicatricial alopecia are further classified by the type of inflammatory cells that destroy the hair follicle during the active stage of the disease. The inflammation may predominantly involve lymphocytes or neutrophils. Cicatricial alopecia that predominantly involve lymphocytic inflammation include lichen planopilaris, frontal fibrosing alopecia, chronic cutaneous lupus erythematosus, central centrifugal alopecia, pseudopelade (Brocq), alopecia mucinosa, and keratosis follicularis spinulosa decalvans.
The causes of the cicatricial alopecia are not completely known. However, all cicatricial alopecia involve inflammation directed at the hair follicle, the upper part of the follicle where the stem cells and sebaceous gland are located are generally involved. Permanent hair loss occurs when the stem cells and the sebaceous glands are destroyed. This type of hair loss is usually irreversible.
Sometimes the inflammation shifts from a predominantly neutrophilic process to a lymphocytic process. Cicatricial alopecia with a mixed inflammatory infiltrate include folliculitis keloidalis and erosive pustular dermatosis.
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